Welcome!

to King's Genomics 

██████╗ ██╗ ██████╗ ██╗███╗   ██╗███████╗ ██████╗ ██████╗ ███╗   ███╗ █████╗ ████████╗██╗ ██████╗███████╗
██╔══██╗██║██╔═══██╗██║████╗  ██║██╔════╝██╔═══██╗██╔══██╗████╗ ████║██╔══██╗╚══██╔══╝██║██╔════╝██╔════╝
██████╔╝██║██║   ██║██║██╔██╗ ██║█████╗  ██║   ██║██████╔╝██╔████╔██║███████║   ██║   ██║██║     ███████╗
██╔══██╗██║██║   ██║██║██║╚██╗██║██╔══╝  ██║   ██║██╔══██╗██║╚██╔╝██║██╔══██║   ██║   ██║██║     ╚════██║
██████╔╝██║╚██████╔╝██║██║ ╚████║██║     ╚██████╔╝██║  ██║██║ ╚═╝ ██║██║  ██║   ██║   ██║╚██████╗███████║
╚═════╝ ╚═╝ ╚═════╝ ╚═╝╚═╝  ╚═══╝╚═╝      ╚═════╝ ╚═╝  ╚═╝╚═╝     ╚═╝╚═╝  ╚═╝   ╚═╝   ╚═╝ ╚═════╝╚══════╝

Based in Social, Genetic & Developmental Psychiatry Centre at King's College London.

About Us

This is the official homepage of the bioinformaticians at King's Genomics! We turn data into discoveries and genomes into stories.

📊 R 🐍 Python ☁️ Amazon Web Services 🧬 Genome Studio 🐳 Docker 🔍 Analysis

🗃️ Services

Nanopore

Comprehensive analysis of long-read sequencing data using Oxford Nanopore Technologies

📑Direct RNA

Direct RNA sequencing for methylation pattern analysis

Learn more

📑cDNA

cDNA sequencing and analysis

Learn more

📑Adaptive Sequencing

Real-time selective sequencing to enrich targets of interest

Learn more

📑Human Variation Analysis

Detection of SNPs, SVs, CNVs and methylation patterns

Learn more

Microarray

End-to-end microarray data analysis pipeline for genetic association studies

🖇️Quality Control - GenomeStudio

QC raw Illumina genotyping data using the Illumina GenomeStudio software

Learn more

📑Imputation

Reference-based imputation to increase marker density

Learn more

📑GWAS Analysis

Genetic correlation, heritability analysis, and LDSC

Learn more

📑CNV Analysis

Copy number variation detection and analysis

Learn more

📑Methylation Analysis

DNA methylation pattern analysis and interpretation

Learn more

Recent Projects

PRADA

Led by Johan Zvrskovec from Translational Neuropsychiatry Group

Current
  • Supporting setup of adaptive sequencing pipeline
  • Custom tools for matching CPIC guidelines for clinicians

OPERA

Catheryn Lewis Research Group

May 2025- August 2025
  • Quality Control of the Micro-Array Data
  • Imputation using TOP-MED for QC'd data

People

Team

Sang Hyuck Lee

Sang Hyuck Lee

Lead Bioinformatician

He contributed to the GLAD and EDGI studies, leading genotyping data QC, and continues his research on eating disorders as a part-time PhD student at King's College London. And is the primary analyst for the PGCED freeze 3 data.

Bhakti Nagpurkar

Bhakti Nagpurkar

Research Assistant

Collaborator

Dr. Hyunah Lee

Dr. Hyunah Lee

Researcher/Bioinformatician

Dr. Lee is a neuroscientist and geneticist advancing understanding of how genetic variation shapes brain function and vulnerability to mental illness. She has led groundbreaking projects uncovering APOE-mediated mechanisms of neurogenesis in Alzheimer's disease and decoding the genetic architecture of depression, anxiety, and eating disorders in over 17,000 participants.